Salmon Fibrinogen

Description

Salmon Fibrinogen Features

• Excellent proliferation of stem cells & retention of ‘stemness’ (Zhou et al. 2017)
• Superior performance for neurite outgrowth and neuronal cell growth (Ju et al. 2007)
• Reliable selection and growth of tumourigenic cells (Liu et al. 2012)
• More efficient extracellular matrix than human-derived fibrin (Sieminski et al. 2004)
• Slower gel degradation in vitro and in vivo
• Consistent performance in animal hemostasis studies (Rothwell et al. 2005, Floyd et al. 2012)
• Significant reduction of neuro-inflammation (Sharp et al. 2012)

Product is shipped frozen. Upon receipt, store product at -80°C.

Sourced from only vetted farms which use humane practices and strive for sustainability. Fish are fed an organic, non-GMO diet free of antibiotics and pesticides.

General Procedure

1. Gently crush lyophilized material into a fine powder using a spatula or other means, in original vial or after removal into alternate desired container.
2. Add desired amount of sterile de-ionized water. A volume of 4-5 ml is recommended, which will provide a final concentration of 20-25 mg/ml fibrinogen. A smaller amount of water can be used but may result in poor re-hydration.
3. Stir gently and place vial on a rocker for several hours at room temperature, then place at 4-6°C overnight for optimal re-hydration. DO NOT HEAT OR SHAKE. Note: A small amount of insoluble material is normal and can be removed by filtration or centrifugation.
4. After rehydration, store fibrinogen at 4-8°C if planned to be used within 7 days or aliquot and freeze at -80°C. Avoid multiple freeze/thaw cycles, which can weaken clot capability.
5. If sterility is required, filter rehydrated fibrinogen through a 0.22 μm syringe filter before use.

Note: This product is non-sterile.

This product is intended for research and development use only.